The Swiss Armed Forces is using for more than 100 years different kind of horses for special missions.Three breeds are used: Swiss Warmblood horses for riding purposes, Swiss Freiberger horses and mules as "pack horses" for transportation. This article reviews the substances, dosages and routes of administration for simple sedation and anaesthesia in horses and mules, in the field and in a military context. This contribution is also intended for other armies that use mules as the literature is not very rich in this field. Recommendations and indications are given in the form of tables.